The researchers developed a new method to 3D print living skin with a built-in blood vessel from Rensselaer Institute, and this living skin construct is cultured in vitro and transforms into an interconnected microvascular network beneath a layered barrier of skin cells.
Currently, artificial skin grafts can fall off because of the lack of integration with the host cells. In a test conducted on mice, the grafts connect with the animals’ vascular network and turn out to become perfused within four weeks after the transplantation. This development can one day provide new—more functional skin grafts for patients.
But one of the critical challenges for this lack of integration has been the absence of a functional vascular system to assist the transplanted tissue. The skin graft is made by 3D printing using a bioink, including fibroblasts, endothelial cells, pericytes, collagen, and other needed components were leveraged to […]
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