A new study has shown that 3D printing can be used to control stem cell differentiation into embryoid bodies that replicate heart cells.

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Scientists report that they have printed heart cells using additive manufacturing to control stem cell differentiation in embryoid bodies, which are stem cells packed into small cellular aggregates or spheres.

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From the Singapore University of Technology and Design (SUTD), the researchers adopted a multidisciplinary approach by combining the research domains of three-dimensional (3D) manufacturing and life sciences. PhD student Rupambika Das and Assistant Professor Javier Fernandez 3D printed several micro-scaled physical devices with finely tuned geometries. They then used these devices to demonstrate an unprecedented precision in the directed differentiation of stem cells through the formation of embryoid bodies.

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In their study, the researchers successfully regulated the parameters for enhancing the production of cardiomyocytes, cells which are found in the heart. These parameters included cell numbers, […]

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